ISSN 1662-4009 (online)

ey0015.3-3 | Mechanisms of the year | ESPEYB15

3.3 Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

A Godbole , S Lyga , MJ Lohse , D Calebiro

To read the full abstract: Nat Commun 2017;8:443G-protein-coupled receptors (GPCRs) are a large family of receptors localized at the cell membrane, detecting specific ligands such as hormones, neurotransmitters, odors, pheromones. Further, GCPRs are the main element for the photoisomerization process, necessary to convert a photon impulse to an electrical signal in photosensitive gan...